Ritesh Nawkhare
Bangur Institute of Neurosciences, India
Title: Contiguous involvement of brain and spinal cord by plasma cell granuloma – A rare presentation
Biography
Biography: Ritesh Nawkhare
Abstract
Plasma cell granuloma of the Central Nervous System (CNS) is a rare entity. Primary intracranial lymphoma was first reported by West et al. in 1980 with around 60 cases reported till date. Previously reported locations include meninges, cerebral hemispheres, ventricles, hypothalamus, sellar region and cerebellum. Intracranial plasma cell granuloma is characterized radiologically by its extra axial, dural based location and homogeneous enhancement with contrast. Owing to it, meningioma, tuberculoma, sarcoidosis and wegners granulomatosis comprise important differential diagnosis. Plasma cell granuloma is generally a benign, non-recurring lesion. Treatment options for plasma cell granuloma include total/subtotal excision, steroids and radiotherapy. Technically inaccessible sites have been treated with biopsy followed by steroid therapy. In majority of cases a single plasma cell granuloma has been reported in the brain or spinal cord. Only two cases of plasma cell granuloma simultaneously involving the brain and spinal cord have been reported. We believe this is the first case showing a single lesion contiguously involving the brain and spinal cord in its extent and was managed surgically and discuss its clinical, radiological and pathological findings along with review of literature.